Alexandra F Freeman Selected Research

Hematopoietic Stem Cell Transplantation

10/2021	Pulmonary Manifestations of GATA2 Deficiency.
1/2021	Case Report: Fatal Complications of BK Virus-Hemorrhagic Cystitis and Severe Cytokine Release Syndrome Following BK Virus-Specific T-Cells.
1/2021	Daratumumab for delayed RBC engraftment following major ABO mismatched haploidentical bone marrow transplantation.
1/2020	Hematopoietic Stem Cell Transplantation and Vasculopathy Associated With STAT3-Dominant-Negative Hyper-IgE Syndrome.
1/2019	Insights into immunity from clinical and basic science studies of DOCK8 immunodeficiency syndrome.
12/2018	Hematopoietic Stem Cell Transplantation in Primary Immunodeficiencies Beyond Severe Combined Immunodeficiency.
6/2017	Haploidentical Related Donor Hematopoietic Stem Cell Transplantation for Dedicator-of-Cytokinesis 8 Deficiency Using Post-Transplantation Cyclophosphamide.
1/2017	Resolution of Multifocal Epstein-Barr Virus-Related Smooth Muscle Tumor in a Patient with GATA2 Deficiency Following Hematopoietic Stem Cell Transplantation.
1/2016	Food allergies can persist after myeloablative hematopoietic stem cell transplantation in dedicator of cytokinesis 8-deficient patients.
9/2011	Successful allogeneic hematopoietic stem cell transplantation for GATA2 deficiency.

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Alexandra F Freeman Research Topics

Disease

40	Infections 10/2023 - 11/2005
39	Job Syndrome (Hyper-IgE Syndrome) 06/2023 - 11/2005
17	Eczema 01/2021 - 11/2005
10	Reinfection 01/2019 - 11/2005
8	Virus Diseases (Viral Diseases) 11/2022 - 11/2009
8	Primary Immunodeficiency Diseases 01/2020 - 05/2008
7	Neoplasms (Cancer) 10/2023 - 03/2013
7	Eosinophilia 01/2022 - 11/2009
7	Hypersensitivity (Allergy) 01/2020 - 04/2008
6	Inflammation (Inflammations) 05/2024 - 02/2010
6	Dermatitis 01/2019 - 10/2006
5	Scoliosis 01/2021 - 11/2005
5	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 01/2019 - 11/2010
5	Pneumonia (Pneumonitis) 01/2016 - 10/2006
5	Chronic Granulomatous Disease 04/2015 - 11/2004
4	Mycoses (Diseases, Fungus) 03/2024 - 11/2015
4	Lymphopenia (Lymphocytopenia) 01/2021 - 01/2012
4	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2020 - 11/2004
4	Immune System Diseases (Immune Disorders) 01/2019 - 05/2013
4	GATA2 Deficiency 01/2018 - 09/2011
4	Abscess 01/2018 - 12/2010
4	Exanthema (Rash) 01/2012 - 11/2004
3	COVID-19 12/2023 - 07/2020
3	Pulmonary Alveolar Proteinosis 10/2021 - 02/2010
3	Wounds and Injuries (Trauma) 01/2021 - 02/2014
3	Food Hypersensitivity (Food Allergy) 01/2019 - 12/2013
3	Neutropenia 01/2019 - 12/2009
3	Bronchiectasis 09/2017 - 12/2008
3	Anaphylaxis (Anaphylactic Shock) 03/2017 - 12/2013
2	Thymoma (Thymic Carcinoma) 03/2024 - 11/2021
2	autosomal recessive Candidiasis familial chronic mucocutaneous 11/2022 - 10/2016
2	Chronic Mucocutaneous Candidiasis 01/2022 - 04/2016
2	Necrosis 12/2020 - 04/2008
2	Autoimmune Diseases (Autoimmune Disease) 10/2020 - 02/2016
2	Viremia 10/2019 - 03/2012
2	Tuberculosis (Tuberculoses) 01/2019 - 01/2018
2	Common Variable Immunodeficiency 01/2019 - 01/2012
2	Atopic Dermatitis (Atopic Eczema) 01/2019 - 12/2013
2	Immediate Hypersensitivity 01/2019 - 01/2016
2	Lymphoma (Lymphomas) 01/2019 - 07/2014
2	Liver Abscess 01/2018 - 03/2012
2	Craniosynostoses (Craniosynostosis) 09/2017 - 03/2007
2	Warts (Wart) 01/2017 - 03/2012
2	Bacterial Infections (Bacterial Infection) 07/2013 - 05/2008
1	Opportunistic Infections (Opportunistic Infection) 03/2024
1	Hepatomegaly 01/2024
1	Prolidase Deficiency 01/2024
1	Latent Tuberculosis 06/2023
1	Fusariosis 06/2023
1	Chronic Kidney Failure (Chronic Renal Failure) 06/2023
1	Phaeohyphomycosis 11/2022
1	Candidiasis (Moniliasis) 01/2022

Drug/Important Bio-Agent (IBA)

39	Immunoglobulin E (IgE)IBA 06/2023 - 11/2005
13	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2023 - 12/2008
10	Proteins (Proteins, Gene)FDA Link 05/2024 - 11/2010
6	AutoantibodiesIBA 03/2024 - 02/2010
4	CytokinesIBA 05/2024 - 10/2007
4	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2020 - 09/2011
3	AntigensIBA 05/2023 - 04/2008
3	ruxolitinibIBA 01/2021 - 01/2017
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2021 - 06/2017
3	Immunoglobulins (Immunoglobulin)IBA 05/2018 - 02/2010
3	Immunoglobulin M (IgM)IBA 08/2015 - 11/2009
2	Interleukin-23 (Interleukin 23)IBA 03/2024 - 10/2018
2	EnzymesIBA 01/2024 - 07/2013
2	InterferonsIBA 12/2023 - 01/2021
2	Messenger RNA (mRNA)IBA 12/2023 - 10/2023
2	mRNA VaccinesIBA 12/2023 - 11/2021
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 12/2023 - 05/2013
2	Immunoglobulin G (IgG)IBA 10/2023 - 11/2009
2	VaccinesIBA 10/2023 - 11/2021
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2023 - 06/2012
2	Monoclonal AntibodiesIBA 01/2022 - 01/2021
2	Amphotericin B (Amphotericin)FDA LinkGeneric 01/2022 - 05/2007
2	BCG Vaccine FDA Link 12/2020 - 01/2018
2	Antiviral Agents (Antivirals)IBA 11/2020 - 01/2020
2	Biomarkers (Surrogate Marker)IBA 01/2019 - 02/2014
2	Interleukin-10 (Interleukin 10)IBA 12/2018 - 01/2018
2	Interleukin-6 (Interleukin 6)IBA 10/2018 - 10/2007
2	NADP (NADPH)IBA 01/2018 - 04/2015
2	STAT1 Transcription FactorIBA 01/2018 - 04/2016
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 04/2013 - 02/2010
2	DNA (Deoxyribonucleic Acid)IBA 03/2012 - 04/2011
2	Anti-Bacterial Agents (Antibiotics)IBA 03/2012 - 12/2010
1	Interleukin-12 (IL 12)IBA 03/2024
1	Interferon Type IIBA 12/2023
1	ProteomeIBA 12/2023
1	EpitopesIBA 12/2023
1	Inosine Diphosphate (IDP)IBA 10/2023
1	Tumor Necrosis Factor InhibitorsIBA 06/2023
1	GlucansIBA 11/2022
1	dectin 1IBA 11/2022
1	AzolesIBA 01/2022

Therapy/Procedure

15	Therapeutics 01/2022 - 11/2005
10	Hematopoietic Stem Cell Transplantation 10/2021 - 09/2011
7	Transplantation 11/2022 - 12/2009
3	Stem Cell Transplantation 10/2021 - 11/2004
2	Peritoneal Dialysis 06/2023 - 04/2004
2	Drug Therapy (Chemotherapy) 10/2016 - 12/2009
1	Organ Transplantation 10/2023